Have well-developed respiratory systems with lungs
Frogs swallow air into their lungs, where oxygen diffuses into the blood to join with hemoglobin in the red blood cells
Amphibians can also exchange gases through their skin
Reptiles have folded lungs to provide increased surface area for gas exchange
Rib muscles assist lung expansion and protect the lungs from injury
Birds have large air spaces called air sacs in their lungs
When a bird inhales, its rib cage spreads apart and a partial vacuum is created in the lungs
Air rushes into the lungs and then into the air sacs, where most of the gas exchange occurs
Mammals have lungs divided into millions of microscopic air sacs called alveoli
Each alveolus is surrounded by a rich network of blood vessels for transporting gases
Mammals have a dome-shaped diaphragm that separates the thorax from the abdomen, providing a separate chest cavity for breathing and pumping blood
During inhalation, the diaphragm contracts and flattens to create a partial vacuum in the lungs, causing the lungs to fill with air