Females with an absence of X chromosome so XO genotype. 45 chromosomes instead of 46. Affects 1 in 5000 people. Characteristics: Physical - Ovaries don't develop – infertile, Don't develop breasts at puberty – broad 'shield' chest, Low set ears, Webbed neck, Hips not bigger than waist, Retain appearance of pre-pubescent girls. Psychological - Higher than average reading ability, Lower than average spatial, visual + maths skills, Socially immature, Difficulty fitting in.