In 1966, Hofling conducted a study on 22 nurses working in a psychiatric hospital. They were told over the phone to administer 20mg of medication to patients even though they knew that the lethal dose of that medication was 10mg. 21 out of 22 nurses obeyed the instruction but were stopped before it could be administered. When later interviewed, the nurses said that they usually received orders from doctors over the phone who typically got annoyed when questioned.