1. 1799 Sir Humphrey Davy discovered that nitrous oxide (laughing gas) effectively dulled pain
2. 1815 Michael Faraday found ether to be more effective
3. Dr Robert Liston used ether as an anaesthetic
4. 1847 James Simpson discovered that chloroform was an effective anaesthetic
5. Queen Victoria used chloroform in childbirth in 1853
6. Joseph Lister tried to find a way to stop bacteria getting into wounds by soaking bandages in carbolic acid
7. By the 1890s surgery had developed into aseptic surgery which meant removing germs from operating theatres