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General Physiology
Finals
(Lesson-8)
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We can recognize three classes of
environmental stimuli:
1.)Mechanical forces – stimulate
mechanoreceptors
2) Chemicals – stimulate
chemoreceptors
3) Electromagnetic Energy – stimulate a
variety
of
receptors,
including
photoreceptors
➢
Exteroceptors
– are receptors that sense stimuli that arise in the external environment
Interoceptors
– sense stimuli that arise from within the body. These internal receptors
detect stimuli related to muscle length and tension, limb position, pain, blood
chemistry, blood volume and pressure, and body temperature.
Sensory
receptor
cells
typically specialized to detect a single type of stimulus
work via mechanisms that are broadly similar to those used by cells to detect chemical signals
various stimuli types convert them into changes in membrane potential
Classes of Environmental Stimuli
Mechanical
Forces
Chemicals
Electromagnetic
Energy
Mechanical
Forces - stimulates mechanoreceptors
Electromagnetic Energy
- Stimulates a variety of receptor including photoreceptor
Chemicals
- stimulate chemoreceptors
Four-Step Process of Information to CNS
Stimulus
Transduction
Transmission
interpretation
Stimulus
- physical stimulus impinges/affects on a sensory neuron or accessory structure
Transduction
- the stimulus energy is used to produce electrochemical nerve impulses in the dendrites of the sensory neuron
Transmission
- the axon of the sensory neuron conduct action potential energy afferent pathway to the CNS
Interpretiation
- the brain creates a sensory perception from electrochemical event produced by afferent stimulation
Example of Mechanical Force Environmental Stimuli
Pressure
Gravity
Inertia
Sound
Touch
Vibration
Example of Chemical Environment Stimuli
Taste
Smell
Humidity
Example
of Electromagnetic Energy Environmental Stimuli
Light
Heat
Electric
Magnetism
Exteroceptor Sensory Transduction
Stimulus - Taste
Receptor -
Taste
Bud
Cells
Location -
Mouth,
Skin
of Fish
Structure -
Epithelial
Cells with
Microvilli
Exteroceptor Sensory Transduction
Stimulus - Smell
Receptor -
Olfactory
Neuron
Location -
Nasal
Passage
Structure -
Ciliated
Neuron
Exteroceptor Sensory Transduction
Stimulus - Vision
Receptor -
Rod
&
Cones
Cells
Location -
Retina
of the
Eye
Structure -
Array
of
photosensitive
pigments
Interoreceptor Sensory Transduction
Stimulus - Temperature
Receptor -
Hot
&
Cold
Receptors
Location -
Skin,
Hypothalamus
Structure -
Free
Nerve
Ending
Interoreceptor Sensory Transduction
Stimulus - Pain
Receptor -
Nociceptor
Location - Throughout the
Body
Structure -
Free
Nerve
Ending
Interoreceptor Sensory Transduction
Stimulus - Blood Pressure
Receptor -
Baroreceptor
Location -
Arterial
Branches
Structure -
Nerve
Ending
over
thin
part of
Arterial
Wall
Sensory
Transduction
Sensory cells respond to stimuli because they possess stimulus-gated ion channels in their membranes.
A depolarization that occurs in a sensory receptor upon stimulation is referred to as a
receptor
potential.
Cutaneous
receptors
– receptors of the skin that respond to stimuli at the
border between the external and internal environments. Respond to heat, cold, pain, touch, and pressure
Thermoreceptors
– naked dendritic endings of sensory neurons that are
sensitive to changes in temperature: cold & warm
Nociceptors
– the receptors that transmit impulses that are perceived by the brain as pain (stimulus that causes or is about to cause tissue damage)
Mechanoreceptors
– contain sensory cells with ion channels that are sensitive to a mechanical force applied to the membrane.
Proprioceptors
– sensory receptors that provide information about the relative position or movement of the animal’s body parts.
Blood
Pressure
- is monitored at two
main sites in the body. One is the
carotid
sinus,
an enlargement of
the left and right internal carotid
arteries, which supply blood to the
brain. The other is the
aortic
arch,
the portion of the aorta very close to
its emergence from the heart.
Baroreceptors
– highly branched
network of afferent neurons at the
walls of the blood vessels which
detect tension in the walls.
Chemoreceptors
– sensory cells that contain membrane proteins that can bind to particular chemicals in the extracellular fluid.
Taste
buds—collections of
chemosensitive epithelial cells
associated with afferent
neurons—mediate the sense of
taste in vertebrates
four kinds of taste buds
salty
,
sweet,
sour
,
bitter,
and
umami
Cupula –
gelatinous
membrane
Statocyst
– sensory structure in which most invertebrates orient themselves; consists of ciliated hair cells with the
cilia embedded in a gelatinous membrane containing crystals of calcium carbonate (
statoliths).
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