Epithelium-lined pathological cavities, usually filled with fluid, semi-solid material, or cellular debris
Fissural cyst
Also called inclusion cyst, because they arise from embryonic epithelium that become entrapped during embryogenesis
Cysts
Clinically present as a soft or fluctuant swelling
Types of cysts
Odontogenic cysts
Nonodontogenic cysts
Pseudocysts
Neck cysts
Pseudocysts
Differ from true cysts in that they lack an epithelial lining
Nasolabial cyst
Rare developmental soft-tissue cyst that develops in the upper lip in thecanineregion
Theories on the etiology of nasolabial cysts
Fissural cyst arising from epithelial remnants entrapped along the line of fusion of the maxillary, medial nasal and lateral nasal processes
Develop from misplaced epithelium of the nasolacrimalduct
Nasolabial cyst
Appears as a soft-tissue swelling in the mucobuccal fold of the maxilla,lateral to themidline
Occasionally causes nasal obstruction, discomfort, or difficulties in wearing dentures
More common in women, usually between 40 and 50 years of age
In most cases there are no radiographic changes, but resorptionoftheunderlyingbone may occur
Nasopalatine duct cyst
The mostcommonnon-odontogenic cyst of the oral cavity
Nasopalatine duct cyst
Arises from epithelial rests in the incisive foramen
Nasopalatine duct cyst
Appears as a slow-growing soft swelling of the palatine papilla, covered with normal mucosa
May become inflamed and painful due to local infection
Radiographically demonstrates a well circumscribed radiolucency in or near the midline of the maxilla, between and apical to the central incisor teeth
A diameter of 6 mm or smaller in this area is usually considered a normal foramen unless other clinical signs and symptoms are present
Epithelial lining of nasopalatineductcyst
Stratified squamous epithelium
Pseudostratified columnar epithelium
Simple columnar epithelium
Simple cuboidal epithelium
Globulomaxillary cyst
Once considered a fissural cyst, located between the globular and maxillary processes, but now thought to be of odontogenic origin
Globulomaxillary lesion
Appears as a well-defined radiolucency, often producing divergence of the rootsof the maxillarylateralincisor and canineteeth
Radicularcyst and periapicalgranuloma can be ruled out with pulp vitality testing
Oral lympho-epithelial cyst
Uncommon developmental lesion of the oral mucosa
Etiology of oral lympho-epithelial cyst
Probably caused by cystic degeneration of glandular or surface epithelium entrapped in lymphoid tissue during embryogenesis
Orallympho-epithelialcyst
Presents as an asymptomatic, mobile, well-defined nodule, usually firm on palpation and elevated, with a yellowish or whitish color
Size ranges from 0.5 cm to 2 cm in diameter
Most frequent location is the floor of the mouth, followed by the posteriorlateralborder and the ventralsurface of thetongue
Thyroglossal duct cyst
Rare developmental lesion that may form along the thyroglossaltract
Etiology of thyroglossal duct cyst
Remnants of thyroglossal duct epithelium
Thyroglossal duct cyst
Usually located under the hyoidbone but can be located anywhere from the suprasternal notch to the foramen cecum of the dorsal tongue
Intraorally, appears as a painless, fluctuant swelling usually 1–3 cm in diameter, located in the midline of the dorsum of the tongue close to the foramencecum
Occasionally, a fistula may form following infection
Most often diagnosed in patients less than 20 years of age
Epithelial lining of thyroglossalductcyst
Stratified squamous
Columnar
Small intestinal epithelium
Mixture of these
Median mandibular cyst
Once considered a fissuralcyst, but now thought to be of odontogenic origin
Medianmandibularcyst
Appears as a swelling in the midline of the mandible
Radiographically appears as a well circumscribed radiolucency between the twolowercentralincisors in the midline
Epithelial lining of median mandibular cyst
Mainly stratified squamous
Median palatal cyst
Rare fissural cyst that develops from epithelium entrapped along the embryonic line of fusion of lateralpalatalshelves
Medianpalatalcyst
Present as a firm or fluctuant swelling in the midline of the hard palate posterior to the palatinepapilla
Radiographically appears as a well-circumscribed radiolucency in the midline of the hardpalate
Epithelial lining of median palatal cyst
Stratified squamous epithelium
Areas of ciliated pseudostratified columnar epithelium may be present
Dermoid and epidermoidcysts
Represent a simple form of cystic teratoma derivedfromskinepithelium entrapped during embryonic development
Dermoid and epidermoidcysts
Mostly occur in the head & neckregion, primarily in the skinaround the eyes & the anteriorupperneck,extendingsuperiorlyinto the floor of themouth
Present as painless swelling exhibiting a doughy consistency on palpation, and may cause elevation of the tongue and interfere with eating & speaking
Histology of dermoid and epidermoid cysts
Lined by a layer of orthokeratinized squamous epithelium, surrounding by connective tissue capsule
Dermoid cysts also exhibit variable numbers of dermal appendages including hair follicles, sebaceous glands
Stafne bone cyst
Also known as lingualmandibularbone cavity, static bone cavity, and lingual salivary gland defect
An asymptomatic lesion
Stafne bone cyst
Radiographically appears as a solitary radiolucency below the inferior alveolar canal near the angle region of the mandible
The lesion is usually oval and exhibits no growth over long periods of time
The periphery is smooth and symmetric
The lesion is benign, has no growth potential, and a classic radiographic appearance that makes diagnosis without biopsy possible and observation without active intervention the treatment of choice
Submandibular salivary gland depression
An incidental finding, not a true cyst
Submandibular salivary gland depression
Radiographically appears as a small, circular, corticated radiolucency below the mandibularcanal