Explain how the structure of enzyme molecules is related to the effect of pH on the activity of amylase.
• enzymes are protein molecules
• have an active site which has a specific shape
• shape of active site will only match shape of substrate
• starch is substrate for amylase
• at pH values above or below the optimum the shape of active site is changed (in some molecules) so substrate can no longer fit the active site
• at extreme pH values enzyme is denatured so shape of active site is changed so amylase can no longer digest starch so rate of digestion decreases