Generates sleep pressure or the desire to sleep, accumulates in the basal forebrain and cerebral cortex during wakefulness and decreases during sleep, amount in your brain increases the longer you are awake, caffeine mimics adenosine and attaches to adenosine receptors but does not clear adenosine, builds up excessive amount of adenosine which explains why you feel extra sleepy after the caffeine is flushed out (caffeine crash), it takes 5-7hrs to remove 50% of caffeine concentration