The liver plays a tremendous role in directing dead cells and leftover chemicals to the digestive and urinary systems
The liver can't actually escort waste out of your person
The lungs can lend a hand, exhaling carbon dioxide, and the colon will eventually poop out unusable stuff and old cell-parts
Much of your chemical waste still needs to be sorted and disposed of, so the urinary system steps in to bat clean-up
Urinary system
Regulates water volume, ion salt concentrations, pH levels, and influences red blood cell production and blood pressure
Urinary system's main purpose
Filters toxic leftovers from your blood and ferries it out of the body
Most of what's in your blood is totally removed by the kidneys, then your body pulls back what it wants to hold onto, before the rest is sent to the bladder
Metabolizing nutrients, especially protein
Produces ammonia, which is toxic
Liver
Converts ammonia into less-toxic urea, which the kidneys filter out into pee
Dirty, pee-soaked toilets and cat litter boxes smell like ammonia because urea can degrade back into ammonia
Kidneys
Pair of dark red, fist-sized, bean-shaped organs that sit on each side of the spine against the posterior body wall
Retroperitoneal, lying between the dorsal wall and the peritoneum
Layers of the kidney
Cortex
Medulla
Renal pelvis
Kidneys filter about 120 to 140 liters of blood every day
Nephrons
Microscopic filtering units in the kidneys, where the real business of blood-processing and pee-making begins
Nephron function
1. Filtration
2. Reabsorption
3. Secretion
Glomerulus
Tangle of capillaries in the glomerular capsule that allow fluid, waste products, ions, glucose, and amino acids to pass from the blood into the capsule, but block out bigger molecules like blood cells and proteins
Filtrate
The stuff that gets squeezed out of the blood into the glomerulus
Parts of the renal tubule
Proximal convoluted tubule (PCT)
Nephron loop/Loop of Henle
Distal convoluted tubule (DCT)
Proximal convoluted tubule (PCT)
Reabsorbs valuable commodities like ions, glucose, and water back into the blood
Loop of Henle
Creates a salt concentration gradient in the medulla to drive the reabsorption of water
Urea
Used by the kidneys to ramp up the concentration gradient in the medulla, making it more effective at drawing out water from the collecting duct
Urea recycling
Urea escapes the urine, finds its way back into the loop of Henle, and runs the whole course again back to the collecting duct
Tubular secretion
Selectively transports extra waste like hydrogen, potassium, and certain organic acids and bases out of the blood and into the urine
The kidneys filter metabolic waste and balance salt and water concentrations in the blood