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Paper 1
Biol 112
Cell junctions
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Pierre Gasly
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What are the 3 types of cell junctions
Impermeable. Adhesive. Communication.
What are
impermeable
junctions

Tight
junctions
What are the
adhesive
junctions

Adheren
and
Desmoses.
What are the types of
communication
junctions

Gap
junctions and
chemical
synapses.
Impermeable junctions
Prevent
the passage of
molecules
between
adjacent
cells
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Adhesive junctions
Mechanically
hold
cells
together
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Communication junctions
Allow
passage of
small
molecules between
cells
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Tight junctions
Separate
the
apical
and
basal plasma membranes
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Adherens junctions
Connect
the cell to
actin filaments
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Desmosomes
Connect the cell to
intermediate filaments
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Function of adherens junctions
Regulates
intracellular
signalling
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Function of desmosomes
Provide
structural
integrity
by withstanding
mechanical
stress
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Types of desmosomes
Belt
Spot
Hemi-desmosomes
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Hemi-desmosomes
Attach the
base
of the cell to the
basal lamina
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Structure of a gap junction
Pores
made of
connexin
, each cell provides
6
connexins
, and so there are
12
in total
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Permeability of gap junctions
Affected by
changes
in
intracellular
pH
or
Calcium
levels
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What is a tissue
It is made of
specialised
cells with
different
functions
What is the function of epithelial tissue
Protect against
mechanical
injury
Provide a barrier against
microbes
and
fluid
loss
Describe the structure of epithelial cells
Made of sheets of
tightly packed cells.
It can be
simple
[
1
layer] or
stratified
[
Multiple
layers].
Where is epithelial tissue found
On the
outside
of the
body
and as the
lining
of
organs.
What junctions are often found in epithelial tissue
Desmosomes
and
tight junctions.
What type of tissue is this
Simple Squamous epithelium
What type of tissue is this
Stratified
squamous
epithelium
A)
1
What type of tissue is this
Pseudostratified columnar epithelium
What type of tissue is this
Simple columnar epithelium
What type of tissue is this
Cuboidal epithelium
What are thee types of epithelium tissue
cuboidal
Simple columnar
Pseudostratified columnar
Simple squamous
Stratified squamous
What is the main function of connective tissue
To provide
mechanical
strength.
Bind
and
support
tissues.
What are the main types of connective tissue.
Dense.
Loose.
Blood.
Adipose.
What are examples of dense connective tissue
Bone Cartillage
and
tendons
What are the features of dense connective tissue
Provides great
mechanical strength
and
elasticity.
Consits of the
Extracellular matrix
with few
cells.
What is dense connective tissue made of
Fibrous
proteins
Ground
substances
What fibrous proteins are found in dense connective tissue
Collagen
and
Elastin.
What ground substances are found in dense connective tissue
Proteoglycans
What is the function of loose connective tissue
To hold small
glands
and
epithelium
together. It also includes the
basal lamina
of cells.
Desccribe the formation of collagen fibrils
Lateral
interactions form between the
triple helices.
What is the role of
muscle
tissue

To support
movement.
Describe the structure of muscle tissues
They are made of
long
excitable
cells containing
actin
and
myosin
filaments.
What is a myofibril
A division wihin a
muscle
fibre.
It consists of
thin
or
thick
filaments.
What are thin muscle filaments made fo
Actin
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