Intercellular chemical signals are produced within & secreted from endocrine glands but the chemical signals have effects at locations that are away from or separate from the endocrine glands that secrete them
Intercellular chemical signal, produced in minute amounts that is secreted into the interstitial fluid and enters the circulatory system to be transported some distance, and acts on tissues (target tissues) at another site in the body to influence their activity in a specific way