Recognisable personality disorders
Previous injection of non-absorbable filler in the same treatment area
Unrealistic patient expectations
Anticoagulant therapy/bleeding disorders
Use of illegal medication/substance abuse
Intolerance for or allergic to lidocaine or epinephrine
Moderate-to-severe acne/rosacea
Intolerance for or allergic to PLL and/or PCL
Immunologically compromising diseases
Facial and/or scalp eczema or psoriasis
Local or systemic infection
History of keloids or hypertrophic scarring
Acne/rosacea at or near the thread entry/exit points
Uncontrolled diabetes
Pregnancy, breastfeeding
Use of blood thinners