Real scientific inference requires exercising judgment at many levels - about the quality of the data, the adequacy of theory, and alternative explanations
What is true of the sample/population need not be true of the individual, and what is true of the sample need not be true of another sample (even if both are drawn from the same population)
An organizing principle that defines concepts and constructs invoked by theories, research questions worth investigating, and methodologies used to assess these questions
Markedly diminished interest or pleasure in all, or almost all, activities most of the day, nearly every day
Significant weight loss when not dieting or weight gain, or decrease or increase in appetite nearly every day
A slowing down of thought and a reduction of physical movement (observable by others, not merely subjective feelings of restlessness or being slowed down)
Fatigue or loss of energy nearly every day
Feelings of worthlessness or excessive or inappropriate guilt nearly every day
Diminished ability to think or concentrate, or indecisiveness, nearly every day
Recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt or a specific plan for committing suicide
Research and Confirmation Bias: People often seek out information that confirms their beliefs, highlight occurrence of expected or favored events, and minimize occurrence of unexpected or unfavorable events
Benefits of Research Methodologies: Impose control, or structure, over the observations we make, the more structure the more confident we can be about the causal status between events