Brainstem Lesion (Face = ipsilateral sensory motor/, arms & legs have contralateral sensory/motor fallout, Face always affected on side of lesion)
Horizontal Gaze Palsy
Due to pontine lesion affecting CNVI nucleus or stroke causing a lesion on contralateralcerebral hemisphere (frontal eye fields)
Vertical Gaze Palsies
Commonly results from midbrain lesions, usually infarct & tumour
Upward Gaze Palsies
Pupils may be dilated & vertical nystagmus occurs during upward gaze
Physiology of Upward Gaze
Upward & downward gaze depends on input from fibre pathways that ascend from vestibular system through MLF on both sides to 3rd & 4th cranial nerve nuclei
Parinaud Syndrome
Vertical gaze palsy. Dorsal midbrain syndrome, on upward vertical gaze palsy that may result from pineal tumour that compresses the midbrain
Characteristics of Parinaud Syndrome
Impaired Upward gaze
Lid retraction (Coller's sign)
Downward gaze preference (setting sun sign)
Convergence retraction nystagmus
Dilated pupils that respond poorly to light BUT can respond to accommodation (light-near dissociation)