Gels

• Gels

  Suspension, in a water medium of insoluble drugs in a hydrated form wherein the particle size approaches or attains colloidal dimension
• Gels

  • If undistributed for sometime, they may become semisolid or gelatinous with some small amount of water separating on standing
  • If distributed/shaken/agitated, they liquefy
  • Thixotropy
  • There are certain gels that do not liquefy when agitated, which is because of the stabilizing agent used
  • Very fine particle size to achieve large surface and thus maximum adsorption capacity
• Ingredients that may be contained in gels

  • Peppermint oil (works as a flavorant)
  • Glycerin
  • Sorbitol
  • Sucrose
  • Saccharin
  • Other suitable flavor and preservative in a total amount of not exceeding 0.5%
• Aluminum Hydroxide Gel

  Category: Medicated gel
• Aluminum Hydroxide Gel

  Synonyms: Colloidal Aluminum Hydroxide, Amphojel, Alternagel
• Aluminum Hydroxide Gel

  Description of the Final Product: this preparation is a white, viscous preparation from which a small amount of water may be separated on standing, is translucent in a thin layer, affects both red and blue litmus paper slightly but is not reddened by phenolphthalein
• Aluminum Hydroxide Gel

  Uses: it is used primarily as an antacid (without systemic alkalosis) in the management of hyperacidity, peptic ulcer, gastritis, and esophagitis, is also used as a skin protectant and mild astringent, may cause constipation
• Aluminum Hydroxide Gel

  Label: White label with shake well
• Aluminum Hydroxide Gel

  Container: 30 mL wide mouth amber bottle
• Aluminum Hydroxide Gel

  Method of Preparation: Chemical Reaction
• Aluminum Hydroxide Gel

  • produces no systemic alkalosis
  • aluminum compounds decrease the absorption of certain drugs, like tetracycline
  • it can be used as an antidote
  • it also interferes with the defoaming action of simethicone
  • these compounds are also constipating
  • sodium benzoate is used as a preservative
• Aluminum Hydroxide Gel

  • peppermint oil is used as a flavorant
  • sodium carbonate is used as an active ingredient
  • ammonium alum is also considered as an active ingredient
  • the ammonium alum used is already in its hydrated form, called decahydrate form. ammonium alum also has different names such as ammonium aluminium sulfate