Carbon monoxide binds to haemoglobin in red blood cells which reduces the amount of oxygen carried in red blood cells. Tar is a carcinogen which causes cancer. Tar causes cells to mutate and divide rapidly. Smokers cough is caused by the mucus that now collects in the lungs. Bronchitis is when the lining of the bronchioles are swollen due to irritation from the smoke. This means that less air can reach the alveoli so less oxygen is transferred into the blood.