Gene therapy is a potential method to either treat or cure genetic related human illnesses
Anc80 - They used an improved gene therapy vector developed at the Massachusetts Eye and Ear that was identified as ___ which enables the transfer of genes to the inaccessible outer hair cells when introduced into the cochlea
Human gene therapy was actually first realized in 1971 when the first recombinant DNA experiments were planned
viruses - the most common type of vectors are _ that have been genetically changed to carry normal human DNA.
Viruses have evolved a way of encapsulating and transporting their genes to human cells in a pathogenic manner.
The idea of gene therapy is based on correcting a disease at its root; fixing the abnormal genes that appear to lead to certain diseases.
There are essentially two forms of gene therapy.
somatic gene therapy
germ-line gene therapy
Somatic gene therapy involves the manipulation of genes in cells that will be helpful to the patient but not inherited to the next generation
germ-line gene therapy -which involves the genetic modification of germ cells or the origin cells that will pass the change on to the next generation.
Stem cells -are mother cells that have the potential to become any type of cell in the body.
stem cells -One of the main characteristics of _ _is their ability to self-renew or multiply while maintaining the potential to develop into other types of cells.
Stem cells are derived from different sources. Two of which are embryonic and somatic stem cells
embryonic stem cells -The ___ are derived from a four-or-five-day-old human embryo that is in the blastocyst phase of development.
in vitro fertilization -The embryos are usually extras that have been created in ___ clinics where several eggs are fertilized in a tube then implanted into a woman.
somatic stem cells -The ___ are cells that exist throughout the body after embryonic development and are found inside of different types of tissue.
somatic stem cells - These stem cells have been found in tissues such as brain, bone, marrow, blood, blood vessels, skeletal muscles, skin, and the liver.
somatic stem cell these cells remain in a non-dividing state for years until activated by disease or tissue injury
germline therapy - is genetic modification of germ cells that will pass the change on to the next generation.
Gene therapy -is a method that may treat or cure genetic-related human illnesses.