STS FINALS 07

Cards (19)

  • Gene therapy is a potential method to either treat or cure genetic related human illnesses
  • Anc80 - They used an improved gene therapy vector developed at the Massachusetts Eye and Ear that was identified as ___ which enables the transfer of genes to the inaccessible outer hair cells when introduced into the cochlea
  • Human gene therapy was actually first realized in 1971 when the first recombinant DNA experiments were planned
  • viruses - the most common type of vectors are _ that have been genetically changed to carry normal human DNA. 
  • Viruses have evolved a way of encapsulating and transporting their genes to human cells in a pathogenic manner.
  • The idea of gene therapy is based on correcting a disease at its root; fixing the abnormal genes that appear to lead to certain diseases.
  • There are essentially two forms of gene therapy. 
    • somatic gene therapy
    • germ-line gene therapy
  • Somatic gene therapy involves the manipulation of genes in cells that will be helpful to the patient but not inherited to the next generation
  • germ-line gene therapy -which involves the genetic modification of germ cells or the origin cells that will pass the change on to the next generation.
  • Stem cells -are mother cells that have the potential to become any type of cell in the body.
  • stem cells -One of the main characteristics of _ _is their ability to self-renew or multiply while maintaining the potential to develop into other types of cells.
  • Stem cells are derived from different sources. Two of which are embryonic and somatic stem cells
  • embryonic stem cells -The ___ are derived from a four-or-five-day-old human embryo that is in the blastocyst phase of development.
  • in vitro fertilization -The embryos are usually extras that have been created in ___ clinics where several eggs are fertilized in a tube then implanted into a woman.
  • somatic stem cells -The ___ are cells that exist throughout the body after embryonic development and are found inside of different types of tissue.
  • somatic stem cells - These stem cells have been found in tissues such as brain, bone, marrow, blood, blood vessels, skeletal muscles, skin, and the liver. 
  • somatic stem cell these cells remain in a non-dividing state for years until activated by disease or tissue injury
  • germline therapy - is genetic modification of germ cells that will pass the change on to the next generation.
  • Gene therapy -is a method that may treat or cure genetic-related human illnesses.