Angina pectoris - a medical term for chest pain or discomfort due to coronary heart disease.
Angina pectoris - occurs when the heart muscle does not get much blood as it needs.
Symptoms of Angina Pectoris
Uncomfortable pressure
Feeling of fullness
Squeezing or pain in the center of the chest
Discomfort in the neck, jaw, shoulder, back or arm
Nitrates (vasodilators) - relax and widen the blood vessels so more blood flows to the heart.
NITRATES
Nitroglycerin
Preparation of Nitrates
injection
buccal
sublingual pill
translingual spray
sustained-release tablets
capsules
transdermal patch
ointment
NITRATES SIDE EFFECTS
Headaches
Dizziness
Nausea
Lightheadedness
Restlessness
Stomach discomfort
Skin rash
Dry mouth
Blurring of vision
Hypotension
arrhythmia
NITRATES
Sustained-release tablet or capsule should be given on an empty stomach. Swallow the tablet or capsule whole.
NITRATES
For translingual spray: do not shake canister. Spray preferably on or under tongue. Do not inhale spray. Instruct patient to wait at least 10 seconds before swallowing.
NITRATES
Put transdermal ointment onto a non-hairy skin surface. Avoid getting ointment on fingers. Rotate application sites to prevent dermal inflammation and sensitization.
Aspirin - reduces blood clotting, making it easier for blood to flow through narrowed heart arteries. Preventing blood clots can reduce the risk of heart attack.
Give with a full glass of water (240 ml), milk, food or antacid to minimize gastric irritation.
Clot-preventing drugs - make blood platelets less likely to stick together, so blood does not clot. This is recommended if the patient can’t take aspirin.
CLOT-PREVENTING DRUGS
Clopidogrel
Prasugrel
Ticagrelor
SIDE EFFECTS OF ANGINA PECTORIS
Flu-like syndrome
Fatigue
Pain
Arthralgia
Back pain
Chest pain
Edema
HPN
Thrombolytic purpura
Abdominal pain
Dyspepsia
Diarrhea
Nausea
Hypercholesterolemia
Epistaxis
Headache
Dizziness
Depression
Upper respiratory infection
Dyspnea
Rhinitis
Bronchitis
Cough
Rash
Pruritus
CLOT-PREVENTING DRUGS
Do not use in breastfeeding mothers or those who are scheduled for surgery at least 7 days before surgery.
CLOT-PREVENTING DRUGS
NSAIDS - increase risk of bleeding
CLOT PREVENTING DRUGS
Feverfew, garlic, ginger, gingko - herbals that increase risk of bleeding
RANOLAZINE (Ranexa) – this may be prescribed for chronic stable angina that does not get better with other medications. It may be used alone or with other angina medications, such as calcium channel blockers, beta blockers or nitroglycerin.