Multicellular organisms need to supply every cell with oxygen, water and nutrients and to achieve this they need a transport mechanism otherwise diffusion will be too long. The development of a transport system is thus directly related to an organism's surface area:volume ratio. Organisms which have a very large surface area:volume ratio e.g. protozoans, may depend upon diffusion, but as an organism grows bigger, the surface area to volume ratio reduces and this makes a specialised transport mechanism necessary.