The pre-synaptic neuron has synaptic vesicles that contain neurotransmitters. A nerve impulse causes the vesicles to travel down the pre-synaptic terminal where the vesicle fuses with the membrane, causing the neurotransmitters to be released into the synaptic cleft where they diffuse and move toward the post-synaptic terminal, where the neurotransmitters bind to the receptor cells. Once neurotransmitters are binded to the receptors cells they are unbounded and reuptaken by the reuptake proteins into the pre-synaptic neuron.