The failure of the French campaign of 1523, and the failure to follow it up by England meant that relations were already cooling.
In 1525, Charles rejected Henry’s new plan to conquer France, which were inspired by Charles’ decisive victory over Francis at the Battle of Pavia in Italy.
Charles was angry because he knew that the English had been negotiating peace with France beforehand!
1526, Wolsey helped to organize the League of Cognac against the Emperor.
1527 Wolsey negotiated peace with France – Treaty of Greenwich.
Charles further upset after 1527 as Henry begins his long campaign to annul his marriage with Catherine of Aragon, Charles’ aunt.