Counter current flow in the nephron
1. Useful things like glucose or water is reabsorbed in the proximal convoluted tubule
2. In the descending arm of the loop of Henle, water moves out of the tubule into the surrounding tissues
3. As it goes lower in the loop of Henle, more water is lost
4. As the fluid goes up the loop, special channel proteins allow ions to leave into the extracellular fluid
5. Ions continue to leave up the loop while the water left in the descending loop
6. The water leaves through diffusion, osmosis, and aquaporins