Cromwell had been the King’s chief adviser and was in favour of reform.
Cromwell's attempt to link England to Schmalkaldic League of Protestant princes in Germany went badly wrong. Marriage annulled.
Instead Henry married Catherine Howard niece of leading conservative, the Duke of Norfolk.
Cromwell's dominant position had led to the undermining of conciliar government; Norfolk and Suffolk were not unhappy to find an opportunity to get rid if him.
Cromwell was dismissed and executed for treason in 1540.
Cromwell was accused of heresy but his real failure was linked to the disastrous failure of the king's marriage with Anne of Cleves.
Without Cromwell, the reforming party was seriously weakened and the conservative faction around Norfolk and Gardiner moved into the ascendancy.