Some studies have looked into the individuals who don't have ASD but have suffered damage to one or both amygdalas.
Kennedy et al (2009) studied SM. They discovered her preferredpersonal space for interactions was much closer than that of the control group
Whilst she felt perfectly comfortable in very closedistances the controls found them very uncomfortable
Supports the theory as SM + others with amygdala damageexhibitsocial behaviourimpairments similar to those seein in people with ASD
Inconsistent findings
Research on the relationship between amygdala volume + the severity of ASD symptoms has yieldedmixedresults
Some studies in adults show increased volume in those with ASD, while others show decreasedvolume (Pierce et al 2001)
Similarly, in children different studies have reported contrastingfindings with some showing smaller amygdala volume in participants with ASD compared to controls (Herbert et al 2003)
As a result, the role of the amygdala in ASD remains unclear
Indirect rather than direct effects
Important for controlling fear and anxiety-relatedbehaviours, like the body's response to stressful at situations
When the amygdala doesn't workproperly, it can affect how people processfear and anxiety + this can impact their socialskills
Some researchers like Ollendick et al (2009) proposed that anxiety is often observed in people with ASD
Indirect connection between amygdala function + difficulties in socialbehaviour as anxietyprocessing may be abnormal
There isn't solid evidence to show that amygdala is more dysfunctional in ASD compared to other brain areas like hippocampus
Paul et al (2010) looked at two women, one being SM, who had damage only to their amygdala but not other nearby brain regions
These women did have some social behaviour issues, but it wasn't as severe as what's seen in clinically diagnosedASD-amygdalafunctionalone might not explain social behaviourchallenges
The role of brain in ASD is intricate + shouldn't be oversimplified by focusing solely on the amygdala
Findings indicate the connection between multiplebrainstructures might not be involved in ASD