Dietary: High consumption of purine-rich foods, alcohol, and fructose
Lifestyle: Sedentary behaviour, obesity
Medical conditions: Hypertension, diabetes, kidney disease, metabolic syndrome
Medications: Use of diuretics, low-dose aspirin, and certain other drugs
Age and sex: More common in men and in postmenopausal women
Genetic predisposition: Family history of gout or hyperuricemia