Epidemiology, Aetiology, Risk Factors, and Pathophysiology of Atherosclerosis
Epidemiology: Leading cause of cardiovascular diseases worldwide, affects millions of people
Aetiology: Caused by accumulation of fatty deposits (plaques) on inner walls of arteries
Risk Factors: High cholesterol, hypertension, smoking, diabetes, obesity, sedentary lifestyle, diet high in saturated fats
Pathophysiology: Initiation - Damage to endothelial lining of arteries, Progression - Lipid accumulation, inflammation, and plaque formation, Complications - Plaque rupture leading to blood clots, causing heart attacks or strokes
Sympathetic Nervous System: Increases heart rate and blood pressure during stress or physical activity
Parasympathetic Nervous System: Decreases heart rate and promotes rest and digestion
Baroreceptors: Located in the aorta and carotid arteries, detect changes in blood pressure and help regulate it by adjusting heart rate and vessel dilation