body does not respond properly to the production of insulin, so blood glucose levels cannot be controlled
increased blood cholesterol can lead to CHD
long-term alcohol use causes liver cirrhosis (scarring), meaning the liver cannot remove toxins from the body or produce sufficient bile
damages the brain and can cause anxiety and depression
alcohol can pass through the placenta, risking miscarriages, premature births, and birth defects
cigarettes contain carcinogens which can cause lung disease and cancers
chemicals can pass through the placenta, risking premature births and birth defects
carcinogens, such as ionising radiation, and genetic risk can cause cancers