The regulation of the internal conditions of a cell or organism in response to internal and external changes
Importance of homeostasis
Keeps conditions constant for optimal enzyme action and cell functions
Includes control of blood glucose concentration, body temperature, water and ion levels
Automatic control systems
1. Electrical responses using the nervous system
2. Chemical responses using hormones
Endocrine disorders can result from abnormalities in the production, secretion, or action of hormones.
Hormones are chemical messengers produced by various organs or tissues, including the pituitary gland, thyroid gland, adrenal glands, pancreas, ovaries (in females), testes (in males), and placenta.
The endocrine system is made up of glands that secrete hormones into the bloodstream.
Specialised cells - receptors which detect stimuli
Coordination centre -which receive and process information from receptors
Effectors- carry out the responses that restore optimum levels
Nervous system enables humans to respond to their environment and coordinate their behaviour.
Information from receptors passes to the central nervous system
Cns coordinates the response of effectors
Reflex action are automatic and rapid so they can protect the body - do not involve the conscious part of the brain
Pain stimulus detection
1. Receptors detect the pain stimulus
2. Impulses from the receptor pass along a sensory neurone to the CNS
3. An impulse then passes through a relay neurone
4. A motor neurone carries an impulse to the effector
5. The effector (usually a muscle) responds, e.g. to rapidly withdraw a limb away from the source of pain without thought
Neurones are not directly connected to each other
Electrical impulse reaching a synapse
1. A chemical is released
2. The chemical diffuses across the gap
3. This causes an electrical impulse to be generated in the second neurone
Investigating reaction time
1. The experimenter holds a metre ruler from the end
2. The subject has their finger and thumb a small distance apart, either side of the ruler, on the 50cm line
3. The experimenter lets go of the ruler and the subject has to trap it
4. The distance the ruler travels from the 50cm line is measured
Endocrine system is a system of glands that secrete hormones into the bloodstream
Hormones are specific receptors that identify the cells in the organ - organ then produces an effect
Compared to nervous system effects of hormones are slower and act for longer
Pituitary gland in brain = master gland
Thyroid gland controls growth rate and metabolism
Adrenal gland releases adrenalin which prepares body for fight or flight response
Ovaries release oestrogen and progesterone (female sex hormones)
Testes produce testosterone (male sex hormone)
Blood glucose concentration is monitored and controlled by the pancreas
pancreas releases more of the hormone insulin
Insulin causes glucose to move from the blood into the cells.
in liver and muscle cells, excess glucose is converted to glycogen for storage
Type 1 diabetes
cause = pancreas failing to produce sufficient insulin
result= uncontrolled high blood glucose levels
Treated = monitoring blood sugar levels and injecting insulin when they are too high
Type 2 diabetes
caused = by body cells losing the ability to respond to insulin
obesity risk factor
treated = with carbohydrate controlled diet and regular exercise
have to take drugs to control blood sugar levels
In people with type 1 diabetes the insulin lowers the blood glucose level by stimulating the liver to convert it into glycogen
Hormones play roles in controlling human reproduction
During puberty, sex hormones cause secondary sexual characteristics to develop
Oestrogen- main female sex hormone at puberty eggs begin to mature and be released this is called ovulation
Testosterone- main male sex hormone produced by the testes and stimulates sperm reproduction
Progesterone - prepares uterus lining for implantation of fertilised egg if pregnancy occurs
Fsh ( follicle stimulating hormone) secreted by pituitary gland causes eggs to mature in the ovaries in first part of the cycle
Oestrogen- ovaries makes the lining of the uterus grow again after menstruation
LH ( luteinising hormon) pituitary gland stimulates the release of the egg from the ovary