HPA axis: sequence of bodily activity in response to stress (hypothalamus, pituitary gland and adrenal cortex)
In response to continued threat, hypothalamus releases more CRH
Pituitary releases ACTH into the bloodstream towards adrenal glands
Adrenal cortex releases stress hormones including cortisol. Feedback system monitors cortisol, CRH and ACTH production lessened if cortisol levels too high