PHARMA LEC

• Logy


  Greek word to study or science
• Pharmacology


  Study of science dealing with drugs
• First people that record how to use drugs are Chinese people called oriental medicine
• Pen Tsao


  Earliest compilation of drugs, which was written by Emperor Shengnung of china in about 2,700 B.C.
• Code of Hammurabi


  Describe penalties for malpractices of practitioner
• Kahun papyrus


  Oldest record of Egyptian drugs
• Ebers papyrus


  Compilation of diseases conditions and prescriptions
• Hippocrates


  Greatest teacher of medicine, "father of medicine"
• Oaths


  • Human medicine oath – Hippocratic oath
  • Vet – veterinarians oath
• Vis medicatrix nature


  Concept of the healing power of nature, Hippocrates theory
• Aristotle


  Formed the scientific basis of medicine
• Theophrastus


  Systemically classifies medicinal plants
• Carolus Linnaeus


  Established the modern scientific method of naming plants and animals, father of taxonomy
• Dioscorides


  Compiled 1st. Materia medica
• Materia medica


  Old study of pharmacology. Extract medicine from plant then use in diseases
• Galen


  Deals with physiology and materia medica
• Publius Vegetius


  Compiled a treatise that included prescriptions for farm animals, father of veterinary medicine
• Geber Ibn Hjar


  Classified drugs and poison
• Valerius Cordus


  Compiled the 1st pharmacopeia (book with drug compilation)
• William Harvey


  Discovered the circulation of blood and indicated that drug were distributed to various parts of the body by this means
• Christopher Wren


  1630, make the 1st I.V. injection of drugs into a dog
• Alexander Wood


  1850, devised the 1st hypodermic needle and syringe
• Theoprastus Bombastus Von Hohenheim

  Introduced the clinical use of opium or laudanum (from a poppy plant), Also called himself Philippus Aureolus Paracelsus
• Fredrich Serturner


  Isolated the narcotic substance of opium and called it morphine after Morpheus
• Edward Jenner


  Discovered the vaccine against small pox
• Francois Magendie


  Established the foundation for modern pharmacology (drug action, D-R. relationship, drug disposition)
• William Withering


  Observed the use of foxglove (plant) in the Tx of drops
• Rudolph Buchheim


  Established the 1st independent laboratory devoted exclusively to the study of pharmacology, "father of Pharmacology"
• John Abel


  "Father of Pharmacology in U.S"
• Paul Ehrlich


  1910, reported the synthesis of arsphenamine which in an anti-syphilitic drug, anti-trypanosomal drug – for typanosoma evansi, 1st antibacterial drug possessing specificity for invading pathogens, "Father of chemotherapy"
• Syphilis is a sexually transmitted disease that cause difficulty in urination with pus
• Alexander Fleming


  1928, isolated penicillin (1st antibiotic)
• Gerhard Domagk


  1935, isolated sulfanilamide (2nd antibiotic)
• Doisy and Butenandt


  Isolated estrone from female urine
• Butenandt


  Isolated aldosterone from male urine
• Slotta


  Discovered the steroid structure of progesterone
• Kendall


  Isolated thyroxine
• Harrington


  Established the chemical structure of thyroxine
• Banting & Best


  1922, isolated and purify insulin
• John Abel


  Isolated adrenalin