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Paper 3
Biol 143
Experimental design
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Created by
Pierre Gasly
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Cards (27)
What are the two reasearch designs
Observational
and
manipulative
What type of research study is correlation
Observational
What type of research study is descrtiptive
Observational
What type of research sutdy is experimental
Manipulative
Describe an observational study
It looks for
patterns
and associations. But cannot
prove causation.
Describe a manipulative study
The conditions of the participants are
manipulated.
It tests both the
cause
and
effect
of the variables.
It aims to prove
causation.
What are the main princciples of experimental design
Control,
randomization
and
repetition.
What are the features of a good research question
It must be
clear
and
precise.
Why would you choose an observational sutdy of a manipulative one
The data is easier to collect.
It is less likely to have unintended consequences.
What type of data is often used for observational studies
Categorical
What is the downside to manipulative studdies
The manipulations may be impossible or
unethical
to perform.
What is reverse causation
When the response variable affects the
explanatory
variable.
What is a confounding variable
This is something that affects both the
explanatory
and
response
variable.
This means that the response and
explanatory
variables have
no
effect on each other.
What often follows on from observational studies
Manipulative
studies
Why do you use a control in studies
It allows your experiment to be comparative and establish whether the difference is just a random change over time.
It also removes the possibility of the
placebo effect.
Why do you need to be able to replicate results
Because individuals
vary
What are the types of manipulative studies
Randomised controlled trial
[RCT].
Describe a randomised controlled trial
It uses
hypothesis
testing for
causality
and prediction.
The
generalizability
of the results is said to be
sample dependent.
The question would be
pharased
as:
Does the
intervention
work for this sample?
What are the types of observational studies
Meta-analysis
of randomised controlled trials.
Quasi-RCT
known as clinical controlled trials.
Case-control
study.
Cohort study.
Cross sectional
study.
Simple case study
known as a survey.
What type of research design has the highest generalisation
Meta analysis
of randomised
controlled
trials
What type of research design has the lowest amount of generalisation
Single case study
Define the
generalizability
of a study
This describes whether it can be applied to different people such as the
wider
population.
Describe a single case study
It does not examine
causality
or
effects.
It has no
generalizability
as it looks at treating an individual.
Describe a cross-sectional study
It
analyses
the data in a
population
at a
single
point in time.
It has
limited generalizability
and
no causality.
It
aims
to look for an
association
between
two variables.
What is the alternative name for a survet
Cross-sectional study
Describe a cohort study
It looks for an
association
between the
independent
variable and a
negative
outcome, which is the
dependent
variable.
It develops a
causality
hypothesis and so has some
generalizability.
Describe a case-control study
It
compares two sets
of
parameters
in
each group of subjects.
It looks for an
association
between the
parameters
, meaning it has some
generalisability.