Symptoms and Pathology

• Symptoms and Pathology

  
  

  1. Recurrent fever, chills, and sweating (synchronized rupture of red cells) known as paroxysms.

  • Every 36 hours Malignant Tertian Malaria: Plasmodium falciparum

  • Every 48 hours Benign Tertian Malaria: Plasmodium ovale, Plasmodium vivax

  • Every 72 hours Quartan Malaria: Plasmodium malariae
• Symptoms and Pathology

  2. Anemia (red cell destruction), Large spleen and joint pain.
• Symptoms and Pathology

  3. P. falciparum infection is most likely fatal

  Cerebral Malaria: red cells, organisms, and pigment block brain vessels Blackwater Fever: sudden massive intravascular hemolysis resulting hemoglobinuria.
• Plasmodium spp. (Malaria)

  A) Liver Cell

  B) Schizont

  C) Gametocyte

  D) Macrogametocytes

  E) Microgamete

  F) Macrogamete

  G) Ookinete

  H) Oocyst

  I) Sporozoites