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Despite numerous prohibitions against
alcohol
throughout history, it has remained the most popular psychoactive drug in the
Western
world
Like other drugs,
alcohol
produces
physiological
effects that can
impair
functioning
in the short term and cause
devastating
damage
in the long term
Cigarette smoking
is still the leading cause of preventable disease,
disability
, and
death
in the United States
For many people,
nicotine
and alcohol become
addictive
, leading to a lifetime of recovery or to debilitation and death
Alcohol
Intoxicating
ingredient in
fermented
or distilled beverages
Standard drink
The amount of a beverage that typically contains
0.6
ounces of alcohol
Typical serving is
larger
than a single
standard drink
Alcohol metabolism
and
excretion
Transported via the circulatory system and easily moves through most biological membranes
Main site for metabolism is the
liver
About
2–10
percent of ingested alcohol is not
metabolized
in the liver and is excreted unchanged by the lungs, kidneys, and sweat glands
Blood alcohol concentration
(
BAC
)
Ratio of
alcohol
in a person's
blood
by weight
Factors affecting BAC
Body
weight
, percentage of body fat, and
sex
Balance of
alcohol
absorbed and rate of
metabolism
Genetic
factors and
drinking
behavior
BAC
is not affected by exercise, breathing deeply, eating, drinking
coffee
, taking other drugs, or sleep
Approximate BAC and body weight
Chart illustrating BAC an average person of a given
weight
would reach after
drinking
the specified number of drinks in the time shown
Alcohol hangover
Headache, shakiness, nausea, diarrhea, fatigue, and impaired mental functioning
Alcohol poisoning
Drinking large amounts of
alcohol
in a short time can rapidly raise the
BAC
into the lethal range
Using
alcohol
with other
drugs
Alcohol-drug combinations
are a leading cause of
drug-related deaths
Alcohol use
Linked to homicide,
suicide
,
automobile
crashes, and other traumatic incidents
Alcohol
impairment
Can make people
vulnerable
to
violent
crimes
Binge drinking
Associated with increased rates of
sexually
transmitted infections, and it raises the risk of
rape
and other forms of sexual assault
In
2019
, 10,142 Americans were killed in accidents involving
alcohol-impaired
drivers
BAC
Higher doses of
alcohol
are associated with a much greater probability of a
crash
Long-term effects of chronic alcohol misuse
Functioning of the
liver
can be altered, leading to "
fatty liver
," alcohol-associated hepatitis, and cirrhosis
Higher doses elevate
blood pressure
and may weaken the heart muscle
Increases risk of cancers of the mouth,
throat
,
larynx
, esophagus, and breast, as well as colorectal cancer and the most common form of liver cancer
Many people with
alcohol use disorder
(AUD) experience
brain shrinkage
and cognitive impairments, ranging from mild to severe
Average life expectancy among people with AUD is about
15
years less than those who do not have the disorder
Fetal alcohol syndrome (
FAS
)
Lifelong
disability for the
unborn
child
Alcohol-related neurodevelopmental disorder
(
ARND
)
Significant
learning
and
behavioral
disorders
No amount of
alcohol
is considered safe for a pregnant woman or
nursing
mother
The best practices for heart health include no
alcohol
The risk of heart disease increases starting with an average of
seven
drinks a week; the risk increases
rapidly
as more drinks are consumed
Supporting someone with an
alcohol
problem
Helping them obtain information about available resources, such as the
counseling
center and local
Alcoholics
Anonymous groups
Rates of
tobacco
use vary based on
gender
, age, race and ethnicity, and educational level
Who is smoking and who is vaping?
Figure showing smoking and vaping rates by
age
, race/ethnicity,
education level
, and location
Tobacco
The leaves of cultivated
tobacco
plants prepared for smoking,
chewing
, or use as snuff
Nicotine addiction
The primary reason people use
tobacco
Nicotine
A powerful
psychoactive
drug considered by many to be the most physically addicting of the psychoactive drugs
Reaches the
brain
via the bloodstream in seconds, releasing powerful chemical messengers and modulating everyday
emotions
Users may plan their
schedules
around opportunities to satisfy their
nicotine
cravings
Users build up
tolerance
and experience
withdrawal
symptoms
Reasons people use tobacco
Social
and
psychological
factors combine with
physiological
addiction to maintain the
tobacco habit
Many people have established patterns of
smoking
or
vaping
while doing something else
Secondary
reinforcers
: stimuli that are associated with
pleasurable
experiences
Nicotine addiction
The primary reason why people use
tobacco
Nicotine
A powerful
psychoactive
drug
Considered by many to be the most
physically
addicting
of the psychoactive drugs
Reaches the brain via the
bloodstream
in seconds
Releases
powerful
chemical messengers
Modulates
everyday emotions
Loss of control
Users may plan their
schedules
around opportunities to satisfy their
nicotine
cravings
Tolerance
and
withdrawal
Users build up
tolerance
and experience
withdrawal
symptoms
Social and psychological factors
Combine with
physiological
addiction to maintain the
tobacco
habit
Secondary reinforcers
Stimuli that are not necessarily
pleasurable
in themselves but that are associated with other stimuli that are
pleasurable
Genetic
factors play an important role in some aspects of
tobacco
use
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