Giardia intestinalis

• Giardia intestinalis (also G. lamblia, G. duodenalis)

  Infective stage: Cyst

  Diagnostic stage: Trophozoites, cyst

  Mode of transmission:

  + Ingestion of food or water contaminated with cyst,

  + person-to-person contact through oral-anal practices

  + via fecal-oral route
• FLAGELLATES

  Disease:

  + Giardiasis

  + Traveler’s Diarrhea

  + Gay bowel syndrome

  • Steatorrhea: Increased fats in stool
  • Most Common cause of intestinal infection worldwide
  • Only protozoan parasites residing in the small intestine
• FLAGELLATES:

  + Diagnosis stool examination

  + Duodenal aspirate

  + Entero - test (String test)

  + Serological Test
• FLAGELLATES:

  Giardia intestinalis

  + Ovoid in shape

  + 2 nuclei (Immature) to 4 nuclei (Mature)

  + 2 median bodies (Immature) to 4 median bodies (Mature)

  A) Cyst wall

  B) Nucleus 2 to 4

  C) Iodine preparation

  D) Median bodies

  
• FLAGELLATES Giardia intestinalis TROPHOZOITE

  • Pear/teardrop-shaped
  • Falling leaf motility with 4 pairs of flagella
  • Bilaterally symmetrical containing two ovoid/ spherical nuclei
  • Equipped with a ventral/ sucking (Attaches to small intestine villi for nourishment
  • “Old man’s face/ Old man with eyeglasses appearance” someone looking at you (Bailey’s)
• Giardia intestinalis TROPHOZOITE

  A) Basal Bodies

  B) Nucleus

  C) Ventrolateral Flagella

  D) Lateral Crest

  E) Ventral Disc

  F) Median bodies

  G) Anterolateral Flagella

  H) Posterolateral Flagella

  I) Ventral Flagella

  J) Caudal Flagella