Addition of an acetyl group to a histone protein so that gene expression is enhanced
Adenine
One of the nitrogenous bases found in DNA and RNA
Anticodon
A sequence of three bases in a tRNA molecule that binds to a complementary sequence of three bases (the codon) in an mRNA molecule, to specify a particular amino acid during protein synthesis
Chromatin
A tangled network of DNA in the nucleus of a cell that is not dividing
Chromosome
One of the 46 rod-like structures that appear in the nucleus of a human cell at the commencement of cell division
Coding strand
The strand of a DNA molecule that is not used to form mRNA
Codon
The strand of a DNA molecule that is not used to form mRNA
CpG site
A site on a DNA molecule where a cytosine nucleotide is next to a guanine nucleotide, DNA methylation usually occurs at these sites
Cytosine
One of the nitrogenous bases found in DNA and RNA
Deoxyribonucleic acid (DNA)
A molecule in the nucleus of a cell that determines the types of protein a cell can make
DNA ligase
Enzyme that joins short sections of DNA together
DNA polymerase
Enzyme that joins nucleotides together
DNA replication
The production of an identical copy of the DNA
Double helix
The spiral shape of the DNA molecule
Epigenetics
Altering expression of a gene without changing the gene structure
Gene
Section of a chromosome that contains the nucleotide sequence coding for a particular trait
Gene expression
The process where information in a gene is used to make a product
Guanine
One of the nitrogenous bases found in DNA and RNA
Helicase
The enzyme responsible for the separation of DNA strands during replication
Histone
A special protein around which DNA is coiled to form chromatin
Messenger RNA (mRNA)
An RNA molecule that transfers coded information from the nucleus to the ribosomes
Methylation
The addition of a methyl group to a DNA molecule that results in inhibition of gene expression
Mitochondrial DNA (mtDNA)
DNA found in the mitochondria
Nuclear DNA
DNA found in the nucleus
Nucleosome
A length of DNA wound around eight histone proteins
Nucleotide
Units of phosphate, sugar and nitrogen base that make up the DNA molecule
Ribonucleic acid (RNA)
A special molecule that takes the code for amino acids from DNA to the ribosomes
Ribosomal RNA (rRNA)
Nucleic acids that form part of the ribosomes
RNA polymerase
An enzyme that is active during transcription of RNA from DNA
Start codon
The sequence AUG (adenine, uracil, guanine) is the codon for the amino acid methionine; when a ribosome reaches this codon, it starts making protein
Template strand
The strand of a DNA molecule that is used to form the sequence of bases in mRNA and is copied during transcription
Thymine
One of the nitrogenous bases found in DNA
Transcription
The process by which messenger RNA is formed, using the code in a DNA molecule by matching the sequence of nucleotides
Transfer RNA (tRNA)
An RNA molecule that brings amino acids from the cytoplasm to the ribosomes
Translation
The production of a protein using the information coded in the mRNA molecule, another name for protein synthesis
Triplet
A sequence of three bases that is the code for a particular amino acid; also called a base triplet