Cards (85)

    • All cells need a supply of ​oxygen and nutrients to ​survive.​
    • They also need to remove ​waste products, so they do ​not build up and become toxic.​
    • For some organisms, these substances simply diffuse over the surface of the body.​
    • Other organisms require specialised exchange surfaces.​
  • Exchange surface = a specialised area that is adapted to make it easier for molecules to cross from one side of the surface to another.​
  • There are 3 main factors that affect the need for an exchange system:​
    1. Size​
    2. Surface area to volume ratio​
    3. Level of activity​
    • In very small organisms (e.g. single celled), all the cytoplasm is very close to their environment.​
    • Simple diffusion is enough.​
    • Multicellular organisms may have several layers of cells. The bigger the organism, the greater the distance substances need to travel to reach the centre.​
    • This makes the diffusion distance too long.​
    • Diffusion alone would be insufficient to supply the innermost cells.​
    • Small organisms have a small surface area, but they also have a very small volume.​
    • Compared with their volume, their surface area is relatively large. ​
    • They have a large surface area to volume ratio.​
    • This means that they have a large enough surface to supply the organism with the resources it needs, and for waste products to diffuse out.​
    • Although large organisms have a larger surface area, their volume is significantly greater.​
    • As size increases, the volume rises more quickly than the surface area.​
    • Therefore, large organisms have a small surface area to volume ratio.​
    • This makes it even harder to absorb enough oxygen for the needs of the body and remove waste products.​
  • Metabolic rate = the amount of energy transferred by that organism within a given period of time.​
  • Metabolic activity requires oxygen to release energy from food in aerobic respiration.
    • Larger organisms tend to have a higher metabolic rate, so need to exchange lots of materials fast.​
    • Organisms that are very active need to supply their cells with lots of nutrients and oxygen to supply the energy for movement.​
    • This need for energy is increased in animals, such as mammals, that keep themselves warm.​
  • To increase the rate of diffusion, good exchange surfaces have:​
    • A large surface area to overcomes the limitations of the SA:V ratio of larger organisms. This provides more space for molecules to pass through. It is often achieved by folding the walls and membranes involved.​
    • A thin barrier to provide a short diffusion distance. The barrier must be permeable to the substances being exchanged.​
    • A good blood supply and/or ventilation to maintain a steep concentration gradient.​
  • Alveoli
    • Large numbers of small, spherical
    • Increase the surface area
  • Alveolar walls
    • Made of squamous epithelium, which consists of flattened cells
    • One cell thick, which reduces the diffusion distance
  • Alveoli
    • Have a good blood supply to maintain the concentration gradient
  • Alveoli ventilation
    1. Constantly supply oxygen
    2. Remove carbon dioxide
    3. Maintains the concentration gradient
  • Alveoli
    • Warm, so the rate of diffusion stays high
  • Alveoli
    • Contain elastic fibres
    • Allow the alveoli to stretch - increasing the surface area
    • Allow the alveoli to recoil - helping to force air out, thereby maintaining the concentration gradients
  • Inner surface of alveoli
    • Coated in lung surfactant
  • Lung surfactant
    • A phospholipid that coats the surfaces of the lungs
    • Reduces cohesion between water molecules, preventing the alveoli from collapsing
    • Further increases the surface area
  • Elastic recoil = the ability to return to original shape and size following stretching.​
    • Air can pass into the lungs through the nose and along the trachea (windpipe), bronchi, and bronchioles.​
    • Finally, it reaches tiny air-filled sacs called alveoli.​
    • These are the surfaces where the exchange of gases takes place – oxygen diffuses into the blood and carbon dioxide diffuses out.​
  • The gaseous exchange system in mammals consists of the lungs and associated airways that carry air into and out of the lungs.
  • The lungs are a pair of inflatable sacs lying in the chest cavity.​
  • Each of the lungs is enclosed in a double membrane known as the pleural membrane.​
  • The space between the two membranes is called the pleural cavity and is filled with a small amount of pleural fluid.
    • Pleural fluid lubricates the lungs.​
    • It also adheres to the outer walls of the lungs to the thoracic (chest) cavity by water cohesion, so that the lungs expand with the chest while breathing.​
    • Land animals face a constant battle between gas exchange and retaining water.​
    • The inner surface of the alveoli is covered in a thin layer of a solution of water, salts, and lung surfactant. This surfactant reduces the cohesive forces between the water molecules, making it possible for the alveoli to remain inflated.​
    • Oxygen dissolves in the water, then diffuses into the blood.​
    • However, water can also evaporate into the air of the alveoli and is lost as we breathe out.​
  • Nasal Cavity
    • Large surface area and good blood supply – this warms the air as it passes into the body.​
    • Hairy lining – hairs trap dust and bacteria in mucus and prevent them from reaching the lungs, which could cause infection.​
    • Moist surfaces – increases the humidity of the incoming air, this reduces the evaporation of water in the lungs.​
    After passing through the nasal cavity, the air entering the lungs is a similar temperature and humidity to the air already there.
  • Trachea
    • The trachea is the airway that leads from the mouth and nose to the bronchi.​
    • It supported by a layer of cartilage ​that holds the trachea open and ​prevents it from collapsing.
    • The rings are incomplete ​to allow it the bend when ​food is swallowed down the ​oesophagus behind.​Gaps between the cartilage filled by smooth muscle and elastic fibres.​
    • The cartilage, smooth muscle, and elastic fibres hold the trachea open but allow flexibility during inspiration and expiration.​
  • The trachea is lined with:​
    • Goblet cells, which secrete mucus.​
    • Ciliated epithelial ​cells, which move ​the mucus (along ​with trapped dust ​and bacteria) away from the lungs.​
  • The bronchi are extensions of the trachea that split into two for ​the left and right lung
  • Bronchus
    • about 20mm in ​diameter.​
    • Bronchi have a very similar structure to the trachea but smaller.​
    • Cartilage rings hold the pipe open
    • The bronchus split into much smaller tubes called bronchioles.​
    • These are about 1 mm or less in diameter.​
    • All bronchioles contain smooth muscle, which holds them open.​
    • When this smooth muscle contracts, the bronchioles constrict. This reduces the air flow to the lungs.​
    • Larger bronchioles contain plates of cartilage.​
    • They also have goblet cells and ciliated epithelium to trap dust and microorganisms.
    • The smaller bronchioles do not have cartilage, goblet cells, or ciliated epithelium.​
    • They have clusters of alveoli at the end.​
    • The bronchioles are lined with a thin layer of epithelial tissue, making some gas exchange possible.​
  • Active inhalation
    • Diaphragm contracts and flattens.​
    • External intercostal muscles contract, moving the ribcage up and out.​
    • Thoracic volume increases.​
    • Thoracic pressure decreases.​
    • Air flows into lungs (to equalise the pressure difference).​
  • Passive Exhalation
    • Diaphragm relaxes and curves up.​
    • External intercostal muscles relax, moving the ribcage down and in.​
    • Thoracic volume decreases.​
    • Thoracic pressure increases.​
    • Air flow – out the lungs (to equalise the pressure difference) ​
  • Active Exhalation
    • Internal intercostal muscles contract, pulling the ribcage down and in.​
    • Abdominal muscles contract: moving the diaphragm up.​
    • Thoracic volume decreases hard and fast.​
    • Thoracic pressure increases rapidly.​
    • Air flows out of the lungs.​
    • A peak flow meter is a simple device that measures the rate at which air can be expelled from the lungs – forced exhalation.​
    • These are often used by asthmatics to monitor how well their lungs are working.​
    • A vitalograph is a more sophisticated versions of a peak flow meter.​
    • The patient breathes out as quickly as they can, and a graph is produced.​
    • This volume of air is called the forced expiratory volume in 1 second.​