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Sience (UPCAT)
Biology
Genetics and Heredity
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Gregor Mendel
he is the father of genetics
Gregor Mendel
the first to study the science of heredity by analysing the patterns of inheritance, emphasized that genes retain permanent identities
gene
is a portion of DNA that determines a specific trait
Allele
a specific form of a gene
genes
responsible for the expression of traits
alleles
are responsible for the variations in which a given trait can be expressed
Mendel's law of independent assortment
it states that genes do not influence each other with regard to the sorting of alleles
Mendel's law of independent assortment
states that every possible combination of alleles for every gene is equally likely to occur
the first x-ray image of DNA was taken in
1952
by
Rosalind Franklin
using a technique called
X-ray crystallography
The first x-ray image led to the discovery of the DNA structure by
James Watson
and
Francis Crick
Deoxyribonucleic Acid
made up of two chains of nucleotide pairs that encode the genetic information for all living things
DNA structure
two polynucleotide strands wrapped around each other in a double helix
hydrogen bonds
it holds the strands of DNA between bases
Deoxyribonucleic Acid
encodes all genetic information and is the blueprint from which all biological life is created
Transcription
RNA converts the genetic information within the DNA
Translation
a format used to build a protein and then moves it to the ribosomal protein factories
Ribonucleic Acid
it only has one strand and its strands are shorter than DNA
DNA technology
the manipulation of genetic material and is relatively a new branch of biotechnology
Recombinant DNA
the combination of nucleotide sequences from two different sources
genetically modified organisms
created through recombinant DNA techniques that carry artificial introduced genes
transgenic organisms
one that carries artificially introduced genes
human gene therapy
this technique uses a virus that can be modified to include a normal gene that may cure the genetic disease
sequencing
automated machines can now sequence many thousands of DNA nucleotides per hour
genomics
advances in DNA sequencing ushers in this area, the study of complete genome sets
genome mapping
the whole-genome shotgun method involves sequencing DNA fragments from an entire genome and then assembling the sequences
the 24 different chromosomes of the human genome contains about
3 billion nucleotide pairs
and
21000 genes
genome
complete set of genetic instructions made in DNA