= mechanoreceptor which detects pressure and vibrations in the skin.
encapsulated nerve ending surrounded by layers of connective tissue and gel.
within the membrane of the neurone there are sodium ion channels- responsible for transporting sodium across the membrane
the neurone ending has a stretch-mediated sodium channel, when they change shape (stretch) their permeability to sodium also changes.
How a pacinian corpuscle converts converts mechanical pressure into a nervous impulse
1 in its resting state, the stretch-mediated sodium ion channels are too narrow to allow sodium ions to pass through, the neurone has a resting potential.
2 when pressure is applied to the pacinian corpuscle, the corpuscle changes shape which causes the membrane surrounding its neurone to stretch.
3 when the membrane stretches the sodium ion channels present widen so sodium ions diffuse into the neurone
4 the influx of positive sodium changes the potential of the membrane which becomes depolarised. This results in a generator potential.
5 the generator potential creates an action potential (nerve impulse) that passes along the sensory neurone