T5 Coronary Artery Disease REVIEW

• Atherosclerosis shows progressive change in endothelium at what age?

  30 years old.
• What medications can be used for CAD?

  • HMG-CoA reductase inhibitors
  • Niacin
  • Fibric Acid
  • ATP Citrate Lyase inhibitors
  • PCSK9 inhibitors
  • Ezetimibe
• What rare but serious side effects are there for statins?

  Liver damage and myalgia.
• What are side effects of Niacin?

  Severe flushing, pruritis, GI symptoms, orthostatic hypotension.
• What are risks with ATP citrate lyase inhibitors?

  Gout and tendon rupture.
• How should someone with angina be cared for in an acute setting?

  Position upright, apply oxygen, assess heart and breath sounds.
• What is the gold standards to identify and localize CAD?

  Cardiac catheterization.
• What medications are given after a PCI?

  Dual antiplatelet therapy with aspirin and clopidogrel.
• What kind of allergy should be recognized for someone about to undergo a PCI?

  Contrast dye allergy.
• If someone is not a candidate for a PCI, what do they do instead?

  Coronary artery bypass graft (CABG).
• What kind of MI occurs if the coronary artery is partially occluded?

  Non ST elevated myocardial infarction or unstable angina.
• What kind of MI occurs if the coronary artery is completely occluded?

  ST elevated myocardial infarction.
• What are clinical manifestations on the skin of a MI patient?

  Skin is ashen, clammy and cool to the touch, diaphoretic.
• When does MI usually occur?

  Usually in the early morning.
• How long does an MI last?

  Longer than 20 minutes.
• When would someone not feel pain with a MI?

  If they have cardiac neuropathy (diabetes).
• What is pericarditis?

  Inflammation of the pericardium, the sac-like membrane surrounding the heart.
• What is the most common complication of MI?

  Dysrhythmias.
• How can pericarditis be relieved position-wise?

  Sitting in forward position.
• How soon does someone need thrombolytic therapy if no PCI is available for acute coronary syndrome?

  Within 30 minutes.
• How soon does someone with UA or NSTEMI need a PCI?

  Within 12 to 72 hours.
• Is thrombolytic indicated for NSTEMI and STEMI?


  No. STEMI only.