Process of converting mechanical pressure into a nervous impulse in a Pacinian corpuscle
1. No pressure: Stretch mediated sodium ion channels are too narrow, sodium remains outside the membrane, resting potential is maintained
2. Pressure is applied: The layers are distorted causing the stretch-mediated sodium channels to open, sodium ions enter the axon of the sensory neurone
3. Generator potential is established: Influx of sodium ions changes the potential of the axon which causes depolarisation of the membrane, if enough generator potentials are produced, an action potential will be established and a nerve impulse moves along the axon