EOSINOPHILS
Subdecks (1)
Cards (82)
- What is the percentage range of eosinophils in bone marrow?A)4% to 6%B) 1% to 3%C) 7% to 9%D) 0.5% to 1%B) 1% to 3%
- Which cytokine is crucial for eosinophil growth and survival?A)IL-1B) IL-2C) IL-3D) IL-5D) IL-5
- What is the origin of eosinophils?A)Common lymphoid progenitorB) Common myeloid progenitorC) Granulocyte-macrophage progenitorD) Megakaryocyte-erythroid progenitorB) Common myeloid progenitor
- How long does it take for mature eosinophils to emerge from the marrow after the last myelocyte mitotic division?A)1 dayB) 3.5 daysC) 7 daysD) 10 dayB) 3.5 days
- What is the turnover rate of eosinophils per day?A)1.5 × 10^8 cells/kgB) 2.2 × 10^8 cells/kgC) 3.0 × 10^8 cells/kgD) 4.5 × 10^8 cells/kgB) 2.2 × 10^8 cells/kg
- What is the normal half-life of eosinophils in circulation?A)12 hoursB) 18 hoursC) 24 hoursD) 36 hoursB) 18 hours
- Where are the normal destinations of eosinophils in the body?A)Bone marrow and spleenB) Liver and pancreasC) Respiratory, gastrointestinal, and genitourinary tractsD) Brain and heartC) Respiratory, gastrointestinal, and genitourinary tracts
- What is the primary function of eosinophils?A)PhagocytosisB) Immune regulation and response to infectionsC) HemostasisD) Antigen presentationB) Immune regulation and response to infections
- Which degranulation mechanism involves granules fusing together within the eosinophil before releasing contents?A)Classical ExocytosisB) Compound ExocytosisC) Piecemeal DegranulationD) EndocytosisB) Compound Exocytosis
- What role do eosinophils play in thymus function?A) Maturation of T cellsB) Deletion of double-positive thymocytesC) Regulation of B cell proliferationD) Antigen presentationB) Deletion of double-positive thymocytes
- How do eosinophils contribute to the response to parasitic helminth infections?A) By producing antibodiesB) By secreting major basic protein and eosinophil cationic proteinC) By releasing interferonsD) By activating complement systemB) By secreting major basic protein and eosinophil cationic protein
- Which tissue-invading parasites can eosinophils destroy through the secretion of major basic protein and eosinophil cationic protein?A) BacteriaB) VirusesC) FungiD) HelminthsD) Helminths
- In which disorder does the eosinophil count correlate with disease severity?A) DiabetesB) ArthritisC) AsthmaD) HypertensionC) Asthma
- What is the primary mechanism through which eosinophils contribute to airway inflammation in asthma?A) Production of antibodiesB) Secretion of basic proteins, lipid mediators, and cytokinesC) Activation of complement systemD) Inhibition of T cell proliferationB) Secretion of basic proteins, lipid mediators, and cytokines
- How do eosinophils contribute to airway remodeling in asthma?A) By promoting vasodilationB) By secreting growth factorsC) By inducing apoptosisD) By inhibiting fibrosisB) By secreting growth factors
- Which antibody treatment can reduce exacerbations in certain asthmatic patients by targeting IL-5?A) Anti-IL-1B) Anti-IL-2C) Anti-IL-3D) Anti-IL-5D) Anti-IL-5
- What is the role of eosinophils in promoting the proliferation of effector T cells?A) InhibitionB) StimulationC) RegulationD) ApoptosisB) Stimulation
- How do eosinophils regulate mast cells through the release of major basic protein?A) Inhibition of degranulationB) Stimulation of degranulationC) Induction of apoptosisD) Promotion of proliferationB) Stimulation of degranulation
- What is the approximate survival time of eosinophils in specific tissue environments?A) 1-3 daysB) 4-6 daysC) 7-9 daysD) 10-12 daysA) 1-3 days
- Which transcription factors are involved in eosinophil development?A) GATA-1, PU.1, c/EBPB) NF-κB, AP-1, STATC) HIF-1, PPAR, NRF2D) FOXO, Myc, E2FA) GATA-1, PU.1, c/EBP
- At which stage can eosinophils first be identified using light microscopy and Romanowsky staining?A)PromyelocytesB) MyelocytesC) MetamyelocytesD) BandsB) Myelocytes (Early)
- What is a characteristic feature of eosinophil myelocytes?A)Presence of Charcot-Leyden crystal proteinB) Presence of secondary granules with an electron-dense crystalline coreC) Bilobed nucleusD) Extensive secretory vesicleB) Presence of secondary granules with an electron-dense crystalline core
- At which stage can eosinophilic promyelocytes be identified cytochemically?A)Due to the presence of Charcot-Leyden crystal protein in their primary granulesB) Due to the presence of large, pale reddish-orange secondary granulesC) Due to the bilobed nucleusD) Due to extensive secretory vesiclesA)Due to the presence of Charcot-Leyden crystal protein in their primary granules
- What additional organelles are present in eosinophil metamyelocytes and bands?A)Mitochondria and endoplasmic reticulumB) Lysosomes and peroxisomesC) Lipid bodies and small granulesD) Ribosomes and Golgi apparatusC) Lipid bodies and small granules
- Which stage of eosinophil development involves the formation of secretory granules or vesicles?A)Eosinophilic promyelocytesB) Early myelocytesC) Eosinophil myelocytesD) Eosinophil metamyelocytes and bandsD) Eosinophil metamyelocytes and bands
- How do the secondary granules change in eosinophil metamyelocytes and bands?A)They decrease in number and become less distinct.B) They increase in number and become more distinct and refractory.C) They remain the same as in the previous stage.D) They disappear completely.B) They increase in number and become more distinct and refractory.
- Which type of granules are found in eosinophil myelocytes along with large, pale reddish-orange secondary granules?A)Azure granules in blue cytoplasmB) Charcot-Leyden crystal protein granulesC) Secretory granules onlyD) No granulesA)Azure granules in blue cytoplasm
- What is a characteristic feature of mature eosinophils?A)Presence of primary granules onlyB) Presence of a single, round nucleusC) Extensive secretory vesicles that increase upon stimulationD) Lack of secondary granulesC) Extensive secretory vesicles that increase upon stimulation