Krebs

• What does the krebs cycle produce?

  reduced coenzymes and ATP
• What does the Krebs cycle involve?

  a series of oxidation-reduction reactions
• where does krebs cycle reactions take place?

  matrix of the mitochondria
• How often does the Krebs cycle happen?

  • Once for every pyruvate molecule
  • twice for every glucose molecule
• First stage of Krebs?

  • Acetyl CoA (from link reaction) combines with 4C molecule to form a 6C molecule
  • CoA goes back to the link reaction to be used again
• 2nd stage of Krebs?


  • The 6C molecule isconverted to a 5C molecule
  • Decarboxylation occurs, (CO2 removed)
  • Dehydrogenation occurs (hydrogen removed)
  • The hydrogen is used to produce REDUCED NAD from NAD
• 3rd Stage of Krebs?

  • 5C molecule converted to a 4C molecule
  • Decarboxylation & Dehydrogenation occur, producing 1 molecule of reduced FAD and 2 molecules of reduced NAD
  • ATP produced by the direct transfer of a phosphate group from an intermediate compound to ADP
• what is substrate-level phosphorylation?

  when a phosphate group is directly transferred from one molecule to another
• What stage of krebs does substrate-level phosphorylation take place?

  3rd stage
• What is the 4C molecule called?

  Oxaloacetate
• What is the 6C molecule called?

  citrate
• what does dehydrogenation do

  hydrogen is removed
• what is decarboxylation?

  CO2 is removed