L42 Mechanism of hormone action

• 3 ways on how hormones interact with target-cell receptors

  -permissive

  -synergistic

  -antagonistic
• what is hormone ?

  mediator molecule that regulates activity of cells
• state the chemical classes of hormone

  -circulating : linger in blood

  -local : quickly inactivated
• differentiate lipid-soluble and water soluble action

  lipid-soluble : hormone diffuse into cell, activates receptor

  water soluble : hormone diffuse and binds to receptor, activates G protei
• 3 effects of hormone

  -induce synthesis

  -change permeability

  -stimulate transport
• classify hormone based on ts characteristics

  lipid soluble : steroid, thyroid, nitric oxide

  water soluble : amino, protein, eicosanoid
• complete the table

  A) cholesterol

  B) adrenal cortex

  C) decarboxylation

  D) platelets

  E) T3,T4 synthesised

  F) thyroid gland

  G) amino acid

  H) pancreas

  I) neurotransmitter

  J) blood vessel

  K) arachidonic

  L) RBC