L44 Thyroid gland

• describe thyroid gland

  -butterfly-shaped

  -inferior to larynx
• state the shape of follicular cells when inactive and active

  inactive : low cuboidal to squamous

  active : cuboidal to low columnar
• state thyroid hormones

  -thyroxine

  -triiodothyronine (T3)
• state 4 stages of producing thyroid hormone

  -iodide trapping

  -synthesis of thyroglobulin

  -oxidation of iodide

  -iodination of tyrosine
• colloid made up of ?

  -thyroglobulin

  -primary iodine
• Name T3 & T4

  T3: Triiodothyronine

  T4: Thyroxine
• Explain secretion of thyroid hormone

  -T3 and T4 are lipid soluble

  -diffuse through plasma membrane, interstitial fluid,then blood

  -T4 converted to T3 by removal of one iodine

  -T3 mainly used by body cell
• functions of thyroid hormone

  -growth

  -sleep
• differentiate hyperthyroidism and hypothyroidism

  A) Increase

  B) Decrease

  C) Grave's

  D) Hashimoto's

  E) Excitability

  F) Somnolence

  G) Surgical removal

  H) oral ingestion T4 tablet