The plasma membrane that surrounds eukaryotic cells is a dynamic structure composed of two layers of phospholipid molecules interspersed with cholesterol and proteins. Phospholipids are composed of a hydrophilic, or "water-loving", head and two tails, which are hydrophobic, or "water-hating". Tiny gaps in the membrane enable small molecules such as oxygen (upper right) to diffuse readily into and out of the cell.