T11 Leukemia

• About 80% of adult leukemias are what kind?

  AML.
• What is the most common type of leukemia in children?

  Acute lymphoblastic leukemia or ALL.
• What is a common sign present in ALL patients at diagnosis?

  Fever.
• What is a hallmark of chronic myelogenous leukemia?

  Philadelphia chromosome.
• Is the Philadelphia chromosome just in CML?

  No.
• What is the most common leukemia in adults?

  CLL.
• What can leukemic cells infiltrating organs lead to?

  Splenomegaly and hepatomegaly.
• What is leukostasis?

  Leukostasis is the abnormal aggregation of white blood cells in the blood vessels.

  Leukemic white cell count is more than 100,000 uL.
• How do they test for leukemia outside of blood and bone marrow?

  Lumbar puncture and CT scan.
• How often is maintenance for leukemia?

  Every 3 - 4 weeks.
• What medications are given prophylactically in ALL patients to prevent CNS involvement?

  Intrathecal chemotherapy of methotrexate or cytarabine.
• What is a primary complication of someone who gets an allogenic HSCT?

  Graft-versus-host disease or GVHD.