negative feedback

• Negative feedback control

  A mechanism that regulates blood glucose concentration
• Blood glucose concentration is regulated by negative feedback control mechanisms
• Negative feedback system

  1. Receptors detect levels

  2. Information communicated to effectors

  3. Effectors react to counteract change
• Receptors in blood glucose control

  • A and B (alpha and Beta) cells in the pancreas
• Glucagon

  Hormone released by alpha cells
• Insulin

  Hormone secreted by Beta cells
• Effectors in response to hormones

  • Liver cells (response to glucagon)
  • Liver cells (response to insulin)
  • Muscle cells (response to insulin)
  • Fat cells (response to insulin)
• A and B cells in the pancreas act as the receptors
• Liver cells act as the effectors in response to glucagon
• Liver, muscle and fat cells act as the effectors in response to insulin