LESSON 12: Gene Mutation

• mutation - change in a gene's nucleotide base sequence
• genome mutation - chromosome missegregation
• chromosome mutation - chromosome rearrangement
• gene mutation - base pair mutation
• Effects of Mutation

  • happens regularly
  • chemicals and UV radiation can cause mutation
  • many mutations are repaired by enzymes
  • some types of skin cancers and leukemia result from somatic mutations
  • some mutation can improve an organism's survival
• germline mutation - change occurs during the DNA replication that precedes meiosis
• somatic mutation - change happens during DNA replication before mitotic cell division

  • some are responsible for certain cancers