Transport in humans

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  • Why do multicellular organisms need special transport systems
    • Unicellular organisms
    • Transport substances into and out of cells by diffusion/osmosis/transport.
    • Relatively slow
    • Multicellular organisms
    • Transport substances into and out of cells by special transport systems
    • Plants: Xylem and phloem
    • Animals: Blood and lymphatic systems
    • Relatively faster + more effective to support multicellular organisms
  • Circulation system
    • System of tubes with pumps and valves to ensure the one way flow of blood
  • Circulation of vertebrates
    • Double circulation
    • Heart
    • Muscular pump to keep blood circulating throughout the body
    • Fills up with blood when relaxes
    • Squeezes out blood at high pressure when contracts
  • Circulation of vertebrates
    • Blood vessels
    • Directs blood flow around the body
    • Arteries
    • Blood vessels that carry blood away from the heart
    • Large artery that leaves from the left side of the heart is known as aorta
    • Branches into smaller arteries
  • Circulation of vertebrates
    • Blood vessels
    • Arterioles
    • Tiny blood vessels that branches out from arteries
    • Divide + branches out into very tiny blood vessels known as blood capillaries
  • Circulation of vertebrates
    • Blood vessels
    • Blood capillaries
    • Microscopic
    • Found between cells + wall of single layer of flattened epithelial which are partially permeable
    • Branched repeatedly to provide a large surface area
    • Blood pressure lowered
    • Blood flow at a slower speed to more time for exchange of materials
  • Circulatory system of vertebrates
    • Blood vessels
    • Venules
    • Capillaries join to form small veins called venules
    • Veins
    • Venules join to form bigger veins to transport blood towards the heart
  • Double circulation
    • Blood passes through heart twice in one complete circuit
    • Consists of pulmonary + systematic circulation
  • Pulmonary circulation
    • To + from lungs
    • Circulation that links lungs to the heart
    • Pulmonary arteries transports deoxygenated blood from the heart to the lungs at a lower pressure
    • Pulmonary veins transports oxygenated blood from the lungs to the heart
    • Function: Transports deoxygenated blood from the heart to the lungs for gas exchange and transports oxygenated blood from the lungs to the left side of the heart
  • Systematic circulation
    • To + from various body parts except the lungs
    • Circulation of blood around the body except the lungs
    • Aorta + arteries carry oxygenated blood from the left side of the heart to the rests of the body except lungs at a higher pressure
    • Veins + vena cavae transports deoxygenated blood from the rests of the body except the lungs back to the right side of the heart
    • Function: Transports oxygenated blood to rests of the body except lungs + transports deoxygenated blood back to the right side of the heart
  • Advantages of double circulation
    • Blood enters lungs at a lower pressure
    1. Due to thinner muscle walls at right ventricle
    2. Blood flows through lungs at a slower speed, so sufficient time for blood to be well oxygenated before returning back to heart
  • Advantages of double circulation
    • Left ventricles pump oxygenated blood to rests of body at higher pressure
    1. Oxygenated blood reaches tissues more quickly
    2. Helps maintain high metabolic rate of mammals
  • Advantages of double circulation
    • Separates deoxygenated and oxygenated blood
  • Single circulation
    • Blood only passes through heart once in one complete circuit
  • Single circulation
    1. artery
    2. ventricle
    3. atrium
    4. veins
    5. gill capillaries
    6. systemic capillaries
  • Single circulation
    1. Arteries that leave gills transports oxygenated blood to rests of body
    2. Arteries transport deoxygenated blood from heart to gills for gas exchange
    3. Veins carry deoxygenated blood from rests of body to heart
  • Heart
    1. conical in shape
    2. size of a clenched fists
    3. made up of cardiac muscles
    4. located in thoracic cavity between lungs
    5. found between chests bone and vertebral column
    6. surrounded by pericardium
    7. Inner membrane in contact with tissues making up heart
    8. fluid in pericardial membrane reduces friction when heart beats
  • Chambers of heart
    1. Four chambered
    2. Two upper chambers
    3. Has thinner muscular walls as they only force blood into ventricles
    4. Does not need high pressure
  • Chambers of heart
    1. Two lower chambers
    2. Has thicker walls as they pump blood to rests of body
    3. Higher pressure
    4. Right ventricle has thinner walls compared to left ventricle
    5. Only pumps blood to lungs from heart
    6. Left ventricle has thicker walls compared to right ventricle
    7. Pumps blood to rests of body
    8. Requires higher pressure
  • Chambers of heart
    1. Medium septum
    2. Located between right and left sides of heart
    3. Separates oxygenated and deoxygenated blood, and prevents them from mixing
  • Chambers of heart
    1. Superior vena cava
    2. Aorta
    3. Aortic valve
    4. Pulmonary arteries
    5. Pulmonary veins
    6. Left atrium
    7. Bicuspid valve
    8. Left ventricle
    9. Septum
    10. Descending aorta
    11. Right ventricle
    12. Inferior vena cava
    13. Tricuspid valve
    14. Right atrium
    15. Pulmonic valve
    16. Blank one on the left: Pulmonary veins
  • Tricuspid and Bicuspid valve
    1. Known as antrioventricular valves
    2. Point downwards to allow blood to flow easier from atria to ventricles
    3. Chordae Tendineae attached to valve flaps to ventricular walls
    4. Open when pressure in atria higher than ventricles
    5. Close when pressure in ventricles higher than atria
    6. Prevents backflow of blood to atria
    7. Tricuspid valve found between right atrium and ventricle
    8. Bicuspid valve found between left atrium and ventricle
  • Pulmonic and aortic valves
    • Known as semi-lunar valves
    • Ensure that blood flows in the right direction
    • Prevents backflow of blood into the ventricles
  • Coronary arteries
    • Two small coronary arteries emerge from the aorta
    • Coronary arteries transports oxygen and nutrients to heart
    • Coronary veins removes wastes and carbon dioxide from heart
    • Return blood to coronary sinus which opens directly into right atrium
  • Arteriosclerosis
    • Stiffening of arteries/ loss of elasticity
    • Fatty substances are deposited on the inner surface of coronary arteries
    • Narrows lumen of arteries + increases pressure
    • Inner surface of the arteries more rough
    • Increases risk of blood clots called thrombin, being trapped
    • Causes blood flow to decrease, causing insufficient supply of oxygen and nutrients to heart muscles
    • May lead to heart attack and tissue death
  • Coronary heart diseases
    • Arteriosclerosis
    • Factors
    • Genes
    • Obesity
    • Diet of high cholesterol + saturated animal fats
    • Diabetes
    • Emotional stress
    • Smoking
  • Coronary heart diseases
    • Diseases
    • Hypertension
    • Stroke/heart attack
    • Angina
    • Prevention
    • Proper diet
    • Proper stress management
    • Avoid smoking
    • Regular physical exercise
  • Cardiac cycle
    1. Sequence of events in one complete heartbeat
    2. One cycle roughly 0.8 seconds
    3. Short pause between two heartbeats
    4. Rate of heartbeat depends on age and size on individual
    5. Atria and ventricles work alternatively
    6. Diastole = Relaxation
    7. Systole = Contraction
  • The cardiac cycle - (Systole + diastole)
    1. Atrial and ventricular diastole
    2. All chambers relax, filling up with blood, AV valves open
    3. Atrial systole
    4. Atria forces blood into ventricles
    5. Ventricular systole
    6. Ventricles contract, increasing blood pressure
    7. Causes bicuspid and tricuspid valve to close
    8. Prevents backflow of blood into atria
    9. Forces semi-lunar valves to open
    10. Blood flows from right ventricle to pulmonary arch
    11. Blood flows from left ventricle to aortic arch
  • The cardiac cycle (Systole + diastole)
    3. Atrial diastole
    1. Right atrium receives blood from vena cava
    2. Left atrium receives blood from pulmonary veins
    4. Atrial and ventricular diastole
    1. Pressure in ventricles drop, causing semi-lunar valve to close
    2. Prevents backflow of blood into ventricles
    3. AV valves open again
    4. Whole cycle repeats and refilling of blood happens again
  • Coronary arteries
    1. Left main coronary artery
    2. Right coronary artery