The maintenance of a relatively stable internal environment in the body despite changes in the external environment
Stimulus-response model
A model that describes how a system responds to a stimulus
Positive feedback system
A stimulus–response process in which the response increases the stimulus
Negative feedback system
A stimulus–response process in which the response counters the stimulus
Stimulus
An event or molecule that can initiate a response
Receptor
A structure that detects a signal or external change, usually a protein
Modulator
Location where information from receptors is sent to and compared to a set point, and where molecules altering the functioning of an effector are released. Also known as the processing centre
Effector
A molecule, cell, or organ that responds to a signal and produces a response
Hormone
A signalling molecule released from endocrine glands that regulates the growth or activity of target cells
Response
The action of a cell, organ, or organism caused by a stimulus
Transduction
The series of events that occur after the reception of a signal which results in the generation of a response
Conduction
The transfer of heat through physical contact with another object
Convection
The transfer of heat via the movement of a liquid or gas between areas of different temperature
Evaporation
The loss of heat via the conversion of water from liquid to gas
Radiation
The transfer of heat via electromagnetic waves
Metabolism
The set of chemical reactions within cells that help maintain the body’s normal functioning including converting food and drink to energy
Thermoregulation
The homeostatic process of maintaining a constant internal body temperature
Endotherm
An animal that produces the majority of its own heat via metabolic processes
Ectotherm
An animal that obtains heat primarily from the environment, rather than its own metabolic heat
Hypothalamus
A section of the brain in mammals that controls the maintenance of the body’s internal environment
Vasodilation
The widening of blood vessels
Cerebral cortex
The outer layer of the brain that plays a key role in a number of processes including memory, attention, and perception
Arrector pili muscles
Small muscles attached to hair follicles
Skeletal muscle
A type of muscle that is voluntarily controlled and that is usually attached to bones
Vasoconstriction
The narrowing of blood vessels
Brown fat
A type of body fat that is activated when the human body experiences low temperatures
Glucose
A six-carbon carbohydrate that comes from the food we eat
Carbohydrate
A class of biomacromolecules made from monosaccharide monomers consisting of carbon, hydrogen, and oxygen. Also known as saccharides or sugars
Glucose transporter
A group of membrane proteins that transport glucose across the plasma membrane
Glycogen
A polysaccharide of glucose that stores energy. Serves as the main storage of glucose in the body
Glycogenesis
Creating glycogen from glucose
Glycogenolysis
Breaking down glycogen into glucose
Blood plasma
The liquid component of blood that supports blood cells
Blood glucose level
A measure of the amount of glucose present in the blood. Normal homeostatic mechanisms keep blood glucose levels between 4.0 – 7.8 mmol/L
Hyperglycaemia
The state of having blood glucose levels above the normal range (>7.8 mmol/L)
Hypoglycaemia
The state of having blood glucose levels below the normal range (<4.0 mmol/L)
Pancreas
An organ of the digestive and endocrine system that releases both digestive juices and hormones
Islets of Langerhans
Regions of the pancreas that contain cells that secrete hormones
Alpha cells
Cells that occupy the islets of Langerhans and secrete glucagon
Beta cells
Cells that occupy the islets of Langerhans and secrete insulin